Oregon State University: OSU research shows hemp compounds can block coronavirus from entering human cells

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Using a mass spectrometry-based screening technique developed in van Breemen’s laboratory, van Breemen and colleagues, including scientists from Oregon Health & Science University, discovered two cannabinoid acids that bind to the SARS-CoV-2 spike protein, preventing the virus from infecting people.

The compounds are cannabigerolic acid (CBGA), and cannabidiolic acid (CBDA), and according to van Breemen, these cannabinoid acids are plentiful in hemp and many of its extracts. “They are not controlled substances like THC, the psychoactive ingredient in marijuana, and have a good safety profile in humans. And our research showed the hemp compounds were equally effective against variants of SARS-CoV-2, including variant B.1.1.7, which was first detected in the United Kingdom, and variant B.1.351, first detected in South Africa.” Additionally, he notes that compounds that inhibit virus-receptor interaction have aided patients with other viral infections such as HIV-1 and hepatitis.

Although resistant variants may still emerge due to the widespread use of cannabinoids, Bremen claims that the combination of vaccination and CBDA/CBGA treatment should foster a much more difficult environment for SARS. -CoV-2. More on the article by Steve Lundeberg can be viewed here.

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